中国临床心理学杂志

记忆对冲突性负波N270及反应时和正确率的影响

作者：欧阳取平¹ 王玉平²

单位：1. 中国医科大学北京顺义医院神经内二科北京 101300
2. 首都医科大学宣武医院神经内科北京 100078

分类号：R395.1

出版年,卷(期):页码：2009,17(2):188-190

摘要：

目的：研究记忆对冲突性负波N270及反应时和正确率的影响。方法：实验中有数字-符号联想作业和数字-数字比较作业两种任务。实验中存在下面四种情况：①数字-符号对应；②数字-符号非对应；③数字-数字匹配；④数字-数字不匹配。呈现的第一个刺激(S1)为数字，随后呈现的第二个刺激(S2)为数字或符号，要求受试者判断S2是否与S1对应或匹配。结果：在冲突状态下，均可诱发出冲突性负波N270，且在数字-数字不匹配状态下比在数字-符号非对应状态下诱发出的N270波幅更负。同时还发现数字-符号联想作业的反应时间比数字-数字比较作业的反应时间明显延长以及数字-数字比较作业的正确率比数字-符号联想作业的正确率明显提高的现象。结论：工作记忆负荷量的增大会影响冲突监测处理过程，从而相应地反映在N270波幅的变化上，同时也会引起正确率和反应时等行为学指标相应的改变。

Objective: To study the effects of memory on the event-related potential N270, the correct reponse rates (CR) and the mean reaction time(RT). Methods: The test included two tasks: the task of the digit-symbol association study and the task of the digit-digit comparison. There were four types of stimulus pairs which were randomly presented to the subjects: ①the symbol(S2) was related to the digit(S1), ②the symbol(S2) was unrelated to the digit(S1), ③the second digit (S2) was matched with the first digit (S1), ④the second digit (S2) was mismatched with the first digit (S1). Subjects were asked to determine if the second stimulus(S2) was related(or matched) with the first stimulus(S1) according to the memory, while event-related potentials(ERPs) were recorded from their scalp. Results: N270 was evoked by the stimulus pairs that contained conflict, but not by the no conflict pairs. Furthermore, the mean amplitudes of N270 elicited by digit-digit con-flict were significantly larger than those elicited by digit-symbol conflict. The reaction times (RTs) in the task of the digitsymbol association session were significantly longer than those in the digit-digit matching session(P<0.05). The correct re ponse rates(CR) in the task of the digit-digit matching session were significantly higher than those in the digit-symbol as sociation session (P<0.05). Conclusion: The working memory system could influence the system of the conflict monitoring and processing system. The course of the conflict monitoring and processing could be effected by the capacity of the working memory. Finally the capacity of the working memory would lead to the change of the mean amplitude of N270, the reaction times (RTs) and the correct reponse rates (CR).

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作者简介：

参考文献：

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