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Mattis痴呆评定量表(中文版)的效度分析
作者:郭起浩  洪震  吕传真  于欢  丁玎 
单位:复旦大学附属华山医院神经内科 上海 200040 
关键词:痴呆 阿尔茨海默病 效度 
分类号:G449.5
出版年,卷(期):页码:2004,12(3):237-238
摘要:

目的:检验Mattis痴呆评定量表(DRS)中文版用于阿尔茨海默病(AD)检测的效度。方法:应用DRS、简易智能状态检查(MMSE)和临床痴呆评定量表(CDR)评定正常老人104例和同时符合DSM -Ⅳ与NINCDS -ADRDA很可能AD诊断标准的AD患者61例。结果:DRS的所有因子分与总分均有显著相关性 ;DRS因子分、总分与MMSE总分显著相关 ;AD组DRS总分与CDR显著相关 ;以不同教育程度分组制定DRS总分的划界分,诊断AD的敏感性为85%~ 94%,特异性为 90%~ 94%。结论:DRS中文版可以用来识别AD患者并判断其认知损害的严重度。

Objective:To assess clinical validity of the Chinese version of Mattis Dementia Rating Scale(DRS) in differentiating dementia of Alzheimer type(AD).Methods:Administered the DRS,mini-mental state examination(MMSE) and clinical dementia rating(CDR) to 61 outpatients with AD and 104 healthy elderly subjects in Shanghai.Results:There was significant correlation between DRS and the total score ,and DRS and MMSE.DRS of the AD grouPhad significant correlation with CDR.Its significant correlation with CDR suggested satisfactory concurrent validity of the scale.The optimal DRS cutoff score for AD according to education level revealed a sensitivity of 85%~94% and a specificity of 90%~94%.Conclusion:The DRS is a clinically valid test for the detection of AD and its severity of cognitive impairment.

基金项目:
作者简介:
参考文献:

[1] Chan AS, Choi MK,Salmon DP.The effects of age, education, and gender on the Mattis dementia rating scale performance of elderly Chinese and American individuals.Journal of Gerontology: Psychological sciences,2001, 56B(6):356-363
[2] 郭起浩,陈瑞燕,洪震,等.不同文化背景下正常老人认知功能比较.中国心理卫生杂志,2003,17(11):731-733
[3] Monsch AU, Bondi MW, Salmon DP, et al.Clinical validity of the Mattis dementia rating scale in detecting dementia of the Alzheimer type.Arch Neurol,1995,52:899-904
[4] Schmidt R, Freidl W, Fazekas F,et al.The Mattis dementia rating scale: normative data from 1001 heaithy volunteers.Neurology,1994,44:964-966
[5] Chan AS, Choi A, Chiu H, et al.Clinical validity of the Chinese version of Mattis dementia rating scale in differentiating dementia of Alzheimer's type in Hong Kong.JINS, 2003, 9:45-55
[6] 郭起浩,洪震,吕传真.阿尔茨海默病的常用神经心理评定量表评介.中华神经科杂志,2003,36(4):310-312

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