Objective:To explore the possible factors that affect the mental health of military officers and soldiers in Tibet and provide the basis for the prevention of mental disorder and the practice of mental intervention.Methods: 90 Symptoms Check List (SCL-90),Life Events Scale(LES) and self-made questionnaire for general condition were used to investigate 299 army officers and soldiers who stationed in the frontier post of Tibet. The subjects were chosen in the principle of cluster sampling in squad or platoon.Results: The factors of environment satisfaction, negative live events, ways of entering Tibet, total score of life events, army years and age were positively related with SCL-90, while the hometown living condition had significantly negative relation with SCL-90. The factors of environment satisfaction, negative life events,army years, motivation of joining the army, ways of entering Tibet and hometown living condition were in the regression equation(P0.05).Conclusion: Multiple factors influence the mental health of army officers and soldiers. The major influential factors include environment, negative life events, the army years, motivation of joining the army, ways of entering Tibet and hometown living condition.