Objective: To get the information of personality of High-school students and its relationship with sex, city and countryside difference. Methods: 402 High-school students were investigated with 16PF. Results: ①10 factors of 16-PF are different in males between city and countryside, for example apprehension, 11 factors of 16-PF are different between are females city and countryside, for example, rule-consciousness.②4 factors of 16-PF, such as independence different between male and female in city. 12 factors of 16-PF, such as sensitivity, are different between male and female in countryside. Conclusion: The distinct difference of personality exists not only between male and female students, but also between city and countryside students.