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青年男性暴力犯罪高危因素与血浆5-HT水平相关性研究
作者:蒋少艾1  方冰2  王小平1  周建松1  徐莉萍3  李凌江1 
单位:1. 中南大学湘雅二医院精神卫生研究所 湖南 长沙 410011 
2.
 湖南省人民检察院 
3.
 广州市脑科医院 
关键词:暴力行为 MMPI 减点-攻击反应测试 5-羟色胺 
分类号:R395.1
出版年,卷(期):页码:2006,14(3):250-251
摘要:

目的:探讨青年男性暴力罪犯血浆5-羟色胺(5-HT)浓度与人格特征、减点-攻击反应(PSAP)测试等犯罪高危因素的关系。方法:以122例青年男性暴力罪犯为研究组,30例某职业高中二年级学生为对照组,分别进行明尼苏达多相人格调查表(MMPI)评定、PSAP测试、外周血5-HT浓度检测。结果:研究组与对照组相比,血浆5-HT浓度明显较高(P<0.01);血浆5-HT浓度与MMPI评定中的Pa、Dy、Cn等亚量变分成正相关(P<0.05);与PSAP测试结果中被减分数成正相关,实际得分数成负相关。结论:高血浆5-HT浓度是青年男性暴力犯罪行为的重要生物学指征,并有较好的临床信度。

Objective: To identify the correlation between plasma 5-HT level and the PSAP(point subtraction aggression paradigm) and the score of MMPI subscales. Methods: 122 male violent offenders and 30 controls were assessed by the MMPI, PSAP and plasma 5-HT. Results: Compared to the controls, the male violent offenders had significantly higher plasma 5-HT level; furthermore, the plasma 5-HT level had positive correlation with the MMPI Pa, Dy, and Cn subscale score, and positive correlation with the points subtracted in the PASA, and negative correlation with the net earnings. Conclusion: The high plasma 5-HT concentration is a valid indicator to the violence behavior.

基金项目:
国家自然科学基金资助(项目号:39900049);湖南省自然科学基金资助(项目号:04JJ3108)
作者简介:
参考文献:

[1] Nelson RJ.Molecular basis of aggression.Neurosciences,2001,24:12:713-719
[2] 周建松,王小平,李凌江.五羟色胺系统与攻击行为.国际精神病学杂志,2005,3:174-177
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[6] 王小平,等.男性青年男性反社会人格障碍暴力犯罪多因素对照研究及预测模型的建立.待发表
[7] 郭艳梅,王小平,崔小媛.攻击性住院精神分裂症患者减点-攻击反应测试对照研究.中国行为医学科学,2002,11(5):498-450
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