Objective:To explore the mental health statues of patients with HIV worried well.Methods:①To record the personal data of 72 patients and information they knew about AIDS.②Symptom check-list 90(SCL-90) were assessed to the patients with HIV worried well.③To treat the patients with psychological consultation and treatment mainly, partly with medicines, observe changes during the treatment.Results:Most patients with HIV worried well had middle school culture level(94.4%) , 70(97.2%) patients had or their sex partners had high risk sex, 39(54.2%) patients got the information about AIDS from Internet;Symptom of the disease were complex, the main complains were worry of infected HIV and similar symptoms with AIDS;The factor scores of somatization, force, relationship, depression, anxiety, hostility, worry, crankiness and psychosis in 72 patients were significantly higher than those in Chinese norms(P<0.01) , 38 patients(52.8%) recovered after treatment.Conclusion:The mental health status of HIV worried well patient is abnormal.Discovering reason, personal treatment, active and patient psychological work are effective methods to prevention and treatment.