Objective: To evaluate sensitivity and specificity of supermarket verbal fluency test(VFT) in identifying mild Alzheimer's disease(AD). Methods: 267 AD, 242 control(NC), 41 vascular dementia(VaD) patients received mini-mental status examination(MMSE), supermarket VFT, clinical dementia rating(CDR) scale. Two components-clustering (generating words within subcategories) and switching (shifting between subcategories) were examined. Results: Cutoff scores for different educational level and corresponding sensitivity and specificity for identifying mild AD were: 0-6yrs, 11, 56.5%, 72.5%; 7-12yrs, 12, 75.0%, 72.9% and 12+yrs, 13, 83.1%, 78.4%. Age and education correlated well with VFT performance in NC. AD weakened this correlation. Both clustering and switching contributed to total scores, while the latter seemed more important. VaD group showed significant lower scores in all VFT items than AD patients. Switching decreased more strikingly than clustering. Conclusion: Supermarket VFT is an effective neuropsychological test in dementia screening. Analysis of clustering and switching may be helpful to differential diagnosis of dementia.
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