中国临床心理学杂志

首发抑郁症患者视觉空间返回抑制的研究

作者：高莉玲¹ 汪凯² 董毅¹ 熊祖伦¹

单位：1 安徽省精神卫生中心安徽合肥 230032
2 安徽医科大学第一附属医院神经内科安徽合肥 230022

关键词：返回抑制抑郁症神经机制

分类号：R395.1

出版年,卷(期):页码：2012,20(2):197-199

摘要：

目的:探究首次发病的抑郁症患者视觉通道中返回抑制效应的情况。方法:选用线索-靶子模式的返回抑制实验范式,对29例抑郁症患者和29例健康对照组进行视觉通道测试。结果:抑郁症患者及正常对照组视觉通道中均存在返回抑制效应,抑郁症患者视觉通道的返回抑制效应约在时间间隔为700ms出现,而正常对照组约在时间间隔为300ms出现。结论:抑郁症患者与正常人的视觉通道返回抑制效应神经机制存在不同,抑郁症患者返回抑制效应异常可能与额叶、前扣带回、丘脑等部位的功能异常有关,从而引起注意功能的损害。

Objective: To investigate the inhibition of return in visual channel on first episode depression patients.Methods: A total of 29 individuals with depression were compared with matched 29 health controls on the IOR task whichwas compiled by E-Prime. Results: In the task, both the depression patients and the health controls show the effect ofIOR. The patients' IOR was watched at the time of 700ms, while the health controls' was found at the time of 300.Conclusion: There were significant differences in inhibition of return in visual channel between the patients with depressionand heath controls on neural mechanism. It may have relationship with the functional disorder of frontal lobe, anterior cin -gulate cortex and thalami, which causes the impairment of the attention function.

基金项目：

国家自然科学基金(30870766)

作者简介：

参考文献：

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