1 Schloss P, Williams DC. The serotonin transporter: A primary target for antidepressant drugs. Journal of Psychopharmacology, 1998, 12(2): 115-121
2 Tamminga CA, Nemeroff CB, Blakely RD, et al. Developingnovel treatments for mood disorders: accelerating discovery. Biological Psychiatry, 2002, 52(6): 589-609
3 Ramamoorthy S, Bauman AL, Moore KR, et al. Antidepressant -and cocaine -sensitive human serotonin transporter: Molecular cloning, expression, and chromosomal localiza tion. Proceedings of the National Academy of Sciences,1993, 90(6): 2542-2546
4 Heils A, Teufel A, Petri S, et al. Allelic variation of humanserotonin transporter gene expression. Journal of Neurochemistry, 1996, 66(6): 2621-2624
5 Ogilvie AD, Battersby S, Fink G, et al. Polymorphism inserotonin transporter gene associated with susceptibility tomajor depression. Lancet, 1996, 347(9003): 731-733
6 Lesch K P, Bengel D, Heils A, et al. Association of anxietyrelated traits with a polymorphism in the serotonin trans porter gene regulatory region. Science, 1996, 274 (5292):1527-1531
7 Collier DA, Stöber G, Li T, et al. A novel functional polymorphism within the promoter of the serotonin transportergene: Possible role in susceptibility to affective disorders. Molecular Psychiatry, 1996, 1(6): 453
8 Hoefgen B, Schulze TG, Ohlraun S, et al. The power of sample size and homogenous sampling: Association betweenthe 5 -HTTLPR serotonin transporter polymorphism andmajor depressive disorder. Biological Psychiatry, 2005, 57(3): 247-251
9 Nobile M, Cataldo MG, Giorda R, et al. A case-control andfamily-based association study of the 5-HTTLPR in pediatric -onset depressive disorders. Biological Psychiatry,2004, 56(4): 292-295
10 Cervilla JA, Molina E, Rivera M, et al. The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: Evidence from the Spanish PREDICT-Gene cohort. MolecularPsychiatry, 2007, 12(8): 748-755
11 Gonda X, Juhasz G, Laszik A, et al. Subthreshold depression is linked to the functional polymorphism of the 5HTtransporter gene. Journal of Affective Disorders, 2005, 87(2):291-297
12 Clarke H, Flint J, Attwood AS, et al. Association of the 5-HTTLPR genotype and unipolar depression: A meta-analysis. Psychological medicine, 2010, 40(11): 1767
13 Gillespie NA, Whitfield JB, Williams B, et al. The relationship between stressful life events, the serotonin transporter(5-HTTLPR) genotype and major depression. PsychologicalMedicine, 2005, 35(1): 101-111
14 Fergusson DM, Horwood LJ, Miller AL, et al. Life stress, 5-HTTLPR and mental disorder: Findings from a 30 -yearlongitudinal study. The British Journal of Psychiatry, 2011,198(2): 129-135
15 Risch N, Herrell R, Lehner T, et al. Interaction between theserotonin transporter gene (5-HTTLPR), stressful life events,and risk of depression. JAMA: the journal of the AmericanMedical Association, 2009, 301(23): 2462-2471
16 宋亚静, 张兰, 殷宏. 5-羟色胺转运体基因多态性和抑郁症的发病 、 性别 、 严重程度及自杀行为的相关性. 西安交通大学学报, 2008, 29(6):674-678
17 范长河, 李雪丽, 贾福军, 等. 中国汉族人群中 5-羟色胺转运体相关多态区基因多态性与抑郁症的关联研究. 中国行为医学科学, 2008, 17(12):1080-1082
18 范娟, 王立伟, 禹顺英, 等. 5-羟色胺转运体基因多态性与青少年抑郁症的关联研究.上海精神医学,2007,19(2):88-91
19 Kendler KS, Karkowski LM, Prescott CA. Causal relationship between stressful life events and the onset of majordepression. American Journal of Psychiatry, 1999, 156(6):837-841
20 Yang J, Yao S, Zhu X, et al. The impact of stress on depressive symptoms is moderated by social support in Chineseadolescents with subthreshold depression: A multi -wavelongitudinal study. Journal of Affective Disorders, 2010, 127(1-3): 113-121
21 Caspi A, Sugden K, Moffitt T E, et al. Influence of lifestress on depression: Moderation by a polymorphism in the5-HTT gene. Science, 2003, 301(5631): 386-389
22 Zalsman G, Huang Y, Oquendo M, et al. Association of atriallelic serotonin transporter gene promoter region(5-HTTLPR) polymorphism with stressful life events and severityof depression. American Journal of Psychiatry, 2006, 163(9): 1588-1593
23 Kim JM, Stewart R, Kim SW, et al. Interactions between lifestressors and susceptibility genes(5-HTTLPR and BDNF) ondepression in Korean elders. Biological Psychiatry, 2007, 62(5): 423-428
24 Hammen C, Brennan P A, Keenan-Miller D, et al. Chronicand acute stress, gender, and serotonin transporter gene environment interactions predicting depression symptoms inyouth. Journal of Child Psychology and Psychiatry, 2010, 51(2): 180-187
25 Karg K, Burmeister M, Shedden K, et al. The serotonintransporter promoter variant (5 -HTTLPR), stress, and de pression meta-analysis revisited: Evidence of genetic moderation. Archives of General Psychiatry, 2011, 68(5): 444-454
26 Chipman P, Jorm AF, Prior M, et al. No interaction between the serotonin transporter polymorphism(5-HTTLPR) andchildhood adversity or recent stressful life events on symptoms of depression: Results from two community surveys. American Journal of Medical Genetics Part B: Neuropsy chiatric Genetics, 2007, 144(4): 561-565
27 Coventry WL, James MR, Eaves LJ, et al. Do 5HTTLPRand stress interact in risk for depression and suicidality? Item response analyses of a large sample. American Journalof Medical Genetics Part B: Neuropsychiatric Genetics,2010, 153(3): 757-765
28 Zhang K, Xu Q, Xu Y, et al. The combined effects of the 5-HTTLPR and 5-HTR1A genes modulates the relationshipbetween negative life events and major depressive disorderin a Chinese population. Journal of Affective Disorders,2009, 114(1-3): 224-231
29 Araya R, Hu X, Heron J, et al. Effects of stressful life ev-ents, maternal depression and 5-HTTLPR genotype on em-otional symptoms in pre - adolescent children. AmericanJournal of Medical Genetics Part B: Neuropsychiatric Ge-netics, 2009, 150(5): 670-682
30 Hankin BL, Jenness J, Abela JRZ, et al. Interaction of 5-HTTLPR and idiographic stressors predicts prospective de-pressive symptoms specifically among youth in a multiwavedesign. Journal of Clinical Child and Adolescent Psycholo-gy, 2011, 40(4): 572-585
31 Eley TC, Sugden K, Corsico A, et al. Gene-environment in-teraction analysis of serotonin system markers with adoles-cent depression. Molecular Psychiatry, 2004, 9 (10): 908 -915
32 Sjoberg R, Nilsson KW, Nordquist N, et al. Development ofdepression: Sex and the interaction between environmentand a promoter polymorphism of the serotonin transportergene. International Journal of Neuro-Psychopharmacology,2006, 9(4): 443-450
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