中国临床心理学杂志

原发性全面强直阵挛患者脑网络的相继故障算法研究

作者：柯铭¹ 曹照¹ 李质婧¹ 杨晓萍²

单位：1. 兰州理工大学计算机与通信学院兰州 730050
2. 兰州军区总医院影像诊断中心兰州 730000

分类号：R395.1

出版年,卷(期):页码：2016,24(4):609-612

摘要：

目的：利用复杂网络相继故障算法探究癫痫病患者功能上的变化。方法：对15例GTCS患者与15例年龄相仿正常志愿者fMRI数据进行建模，依据相继故障算法对重要节点进行攻击，探讨癫痫病患者功能上的改变。结果：与正常对照组相比，癫痫病患者功能上发生了变化，在对重要节点攻击时相继故障较正常对照组的规模更大，而对非重要节点攻击时，较正常对照组鲁棒性更强。结论：癫痫病患者脑区功能发生了异常。

Objective: To explore the changes of function of the human brain in GTCS by using complex network cascading failure algorithm.Methods: The resting-state fMRI data of 15 GTCS and 15 age-mathced normal volunteers were modeled,using cascading failure to attack the important nodes,in order to explore the changes of function in patients with epilepsy.Results: Compared with the normal group,GTCS patients showed functional changes,that the scale of the cascading failures in the attack on the important nodes was larger than normal group,in the attack on the unimportant nodes showed stronger robust than the normal group.Conclusion: Abnormal brain function may ben implicated in patients with epilepsy.

基金项目：

国家自然科学基金（61263047）资助

作者简介：

参考文献：

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