中国临床心理学杂志

癫痫患儿服用丙戊酸钠前后P300认知电位的研究

作者：孟平董选付亚平杨玉霞

关键词：

分类号：R395.2

出版年,卷(期):页码：2000,8(3):181-182

摘要：

癫痫是儿童的常见疾病之一，严重影响患儿的身心健康，对社会及家庭带来不良后果。目前已肯定P300与认知过程有关，是评价认知功能的一个客观电生理指标。本研究用丙戊酸钠治疗癫痫患儿，并用P300来检测其认知功能的变化，现报导如下。

Objective: To assess the cognitive function of epileptic children before and after valproate treatment by use of auditory event-related potentials P300. Methods: 13 patients were tested with auditory event related potentials P300 6 months after treatment. Eight patients were tested after 1-year treatment. Results: there were no statistical differences in the P300 latency, amplitude and reaction time after valproate treatment in epileptic children. Conclusion: There is no significant effect of valproate treatment on the cognitive function of epileptic children.

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参考文献：

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