中国临床心理学杂志

Alzheimer型痴呆临床量表检查与MRI边缘系统体积测量的相关研究

单位：1. 北京医科大学精神卫生研究所北京 100083
2. 北京医科大学第三临床医学院

关键词：Alzheimer型痴呆 MRI 临床量表

分类号：R395.2

出版年,卷(期):页码：2000,8(3):133-135

摘要：

目的:探讨Alzheimer型痴呆海马结构、杏仁核、侧脑室颞角等MRI体积与临床量表检查的相关性。方法:使用Siemens 1.5T超导MRI扫描机,对 2 7例临床诊断Alzheimer型痴呆病人的左右侧海马结构、杏仁核、侧脑室颞角等体积进行定量测量,同时对病人进行临床常用量表的检查。结果:MMSE和WMS与杏仁核、海马旁回总体积和侧脑室颞角体积有高度相关性。结论:脑结构测量与脑功能测量有一定的相关。

Objective: To study the correlation between clinical scale measures and quantitative MRI of hippocampal formation (HF), amygadala (AM) and temporal dementia of Alzheimer's type. Methods: Using Siemens 1.5T superconductive MRI scanning machine, volume measurements of the HF, AM and TH on oblique coronal sections were assessed for 27 cases of dementia of Alzheimer's type. The patients were also administered various clinical scales. Results: The volume of AM, TH and parahippocampals was found to correlate significantly with scores on MMSE and WMS.Conclusion: The volume measurement was found to correlate significantly with function measurement.

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参考文献：

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