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赛乐特治疗广泛性焦虑症门诊患者的开放对照研究
作者:胡岱梅1  孙守宪1  林中2  刘炳伦2 
单位:1. 山东省精神卫生中心 山东济南 250014 
2.
 山东莱芜市复退军人精神病院 
关键词:Paroxetine Doxepine GAD 
分类号:R395.4
出版年,卷(期):页码:2001,9(2):119-120
摘要:

Objective: To compare the effects of the Paroxetine and Doxepine on the out-patients with General Anxiety disorder(GAD). Methods: The out-patients with GAD who met with the CCMD-Ⅱ-R were exposed to one of the two drugs randomly over 4wks, and assessed with HAMA/CGI, TESS. They were also given the laboratory examination of the ECG、GPT、BUN during the therapeutic period. Result: Both groups of out-patients symptoms were gradually relieved at the end of the 2nd week singnificantly and no difference of the both group out-patients were found with HAMA/CGI, The out-patients with the Paroxetine showed less side effects than the Doxepine.Conclusion: Paroxetine would be effecctive and safe in the treatment of GAD.

Objective: To compare the effects of the Paroxetine and Doxepine on the out-patients with General Anxiety disorder(GAD). Methods: The out-patients with GAD who met with the CCMD-Ⅱ-R were exposed to one of the two drugs randomly over 4wks, and assessed with HAMA/CGI, TESS. They were also given the laboratory examination of the ECG、GPT、BUN during the therapeutic period. Result: Both groups of out-patients symptoms were gradually relieved at the end of the 2nd week singnificantly and no difference of the both group out-patients were found with HAMA/CGI, The out-patients with the Paroxetine showed less side effects than the Doxepine.Conclusion: Paroxetine would be effecctive and safe in the treatment of GAD.

基金项目:
作者简介:
参考文献:

[1] Kent JN, Coplan JD, Gorman JM. Clinical utility of the selective serotonin reuptake inhibitors in the spectrum of anxiety. Biol Psychiarty,1998,44:812-824
[2] Gorman JM, Kent JM.SSRIS and SNRIS:Broad spectrum of efficacy beyond major depression.J Clin Psychiatry, 1990,60(Supp14):33-38
[3] 杨德森.神经衰弱研究现状.中华精神科学会神经症与应激相关疾病会议论文集,1999,27-30
[4] Brawman-Mintzer 0,Lydirard RB. Biological basis of generalized anxiety disorder.J Clin Psychiatry,1997,58(Srpp13):16-25
[5] Connor KM,Davidson JRT. Generalized anxiety disorder: Neurobiological and pharmacotherapeutic perspectives. Biol Psychiatry,1998,44:1286-1294
[6] Ballenger JC,Wheadon DE, Steiner M, et al. Double-blind fixed-dose placebo-controlled study of paroxetine in the treatment of panic disorder. Am J Psychiatry,1998,155:36-42
[7] Oehrberg S,Christiansen PE,Behnke K,et al .Paroxetine in the treatment of panic disorder:A randomised double-blind,placebo-controlled study Br. J Psychiatry,1995,167:374-379
[8] Stein MB, Chartier Mj,Hazen AL,et al.Paroxetine in the treament of generalized social phobia:Open-label treatment and double-blind lacebo-controlled dscontinuation.J clin Psychopharmacol,1996,16:218-222
[9] Rocca P,Fonzo V,Scotta M,et al.Paroxetine efficacy in the treatment of generalized anxiety disorer. Acta Psychiatr Scand ,1997,95:444-450
[10] 邹冈.基础神经药理学.北京:科学出版社,1998.177-192

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