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氟哌啶醇与利培酮对精神分裂症患者生活质量的影响
作者:任清涛1  闫加民2  李广3 
单位:1. 山东淄博市精神病医院 山东 淄博 255120 
2.
 山东淄博万杰医院 
3.
 山东淄博卫生学校 
关键词:Schizophrenia Haloperidol Risperidone Quality of life 
分类号:R395.6
出版年,卷(期):页码:2002,10(2):150-151
摘要:

Objective:To compare the effects between haloperidol and rieperidone on quality of life in patients with schizophrenia.Methods:The patients with schizophrenia treated respectively by haloperidol and risperidone were compared by double blind method.The General Quality of Life Inventory (GQOLI) was used to evaluate the life quality,while the Positive and Negative Symptoms Scale (PANSS) and the Treatment Emergent Symptom Scale (TESS) were used to assess the efficacy and side effects.Results:The risperidone group showed better effects than the haloperidol group in the domains of physical function,mental health and social function The difference was significant (P<0.01).Conclusion:The quality of life of Schizophrenic patients treated by haloperidol were poorer than that of risperidone.

Objective:To compare the effects between haloperidol and rieperidone on quality of life in patients with schizophrenia.Methods:The patients with schizophrenia treated respectively by haloperidol and risperidone were compared by double blind method.The General Quality of Life Inventory (GQOLI) was used to evaluate the life quality,while the Positive and Negative Symptoms Scale (PANSS) and the Treatment Emergent Symptom Scale (TESS) were used to assess the efficacy and side effects.Results:The risperidone group showed better effects than the haloperidol group in the domains of physical function,mental health and social function The difference was significant (P<0.01).Conclusion:The quality of life of Schizophrenic patients treated by haloperidol were poorer than that of risperidone.

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参考文献:

[1] 中华医学会精神科学会.中国精神疾病分类方案与诊断标准第2版,南京:东南大学出版社,1995:56-61
[2] 李凌江,郝伟,杨德森,等.社区人群生活质量研究,Ⅲ生活质量问卷的编制.中国心理卫生杂志,1995,9(5):227-231
[3] Spilker B(ed).Quality of life Assessments in Clinical Trials.New York:Raven Press Ltd,1990,237-255
[4] Simpson CJ,Hgde CE,Faragher EB.The Chronicaly mentally ill in community facilities.British Journal of Psychiatry,1989,154(4):77-78
[5] 宋立升,陈美娟,吴晓波,等.社区精神分裂症患者和生活满意度.中国心理卫生杂志,1994,8(2):72-74
[6] 王蕾,李凌江,杨德森,等.社区精神分裂症病人的生活质量对比研究.中国心理卫生杂志,1996,10(4):145-146

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