Objective:To examine the emotional states of asthmatic children with different degrees of severity,as well as the effects of emotion on change of cytokines in airway.Methods:Asthmatic children were divided into two groups according to the degrees of severity:moderate and mild.Their emotional states were measured and results were compared.Correlation analysis was conducted between scores on emotional scales and sputum levels of IL-8.Results:Total scores on anxiety and depression were higher in the moderate group than in the mild group.Negative correlation was found between levels of anxiety and IL-8 during acute exacerbation of asthmatic condition.Conclusion:Emotional distress was found to be increased with severity of asthmatic condition in children.Anxiety contributed to the decreased concentration of IL-8 in asthmatic children's airway.

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