中国临床心理学杂志

语义性痴呆:一例汉语病人的个案研究

作者：郭起浩洪震付建辉于欢吕传真

单位：复旦大学附属华山医院神经内科上海 200040

分类号：R749.1

出版年,卷(期):页码：2003,11(4):253-256

摘要：

目的：分析一例语义性痴呆 (SemanticDementia，SD)患者的神经心理特征。方法：针对一例大学文化程度的SD患者完成一系列神经心理测验和头颅核磁共振(MRI)及氙CT(XeCT)检查。结果：1.语义记忆的选择性损害引起严重的失命名、对口语和书写的词语理解受损、言语流畅性测验表现差以及一般知识的储存丧失；2.语言表达和理解的其他成分相对保持；空间知觉、执行功能和非言语的解决问题能力正常；情景记忆相对保存；3.阅读障碍呈表层失读模式；4.MRI和XeCT提示患者左颞叶新皮层呈现局限性严重萎缩。结论：汉语文化背景的SD患者的认知特征与西方的结果相似，左颞叶新皮层萎缩导致选择性的语义记忆损害。

Objective:To analyze neuropsychological characteristics of a Chinese patient with semantic dementia (SD)。Methods:A patient with SD was selected to finish 11 neuropsychological tests and MRI and XeCT。Results:(1)Selective impairment of semantic memory caused severe anomia, impaired spoken and written single-word comprehension, reduced generation of exemplars on category fluency tests and an impoverished fund of general knowledge; (2)relative sparing of other components of language output and comprehension; normal perceptual skill and non-verbal problem-solving abilities; relatively preserved episodic memory; (3)a reading disorder with pattern of surface dyslexia;(4) radiological investigations (MRI and XeCT) have shown severe left temporal neocortex atrophy.Conclusion:There are similar clinical and neuropsychological characteristics for SD between the Chinese patient and the sample of Western. Selective impairment of semantic memory may bring about by left temporal neocortex atrophy.

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作者简介：

参考文献：

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