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癫痫儿童脑功能成像的临床应用研究进展
作者:乔文达1  董奇1  金真2 
单位:1. 北京师范大学心理学院脑与认知科学研究所 北京 100875 
2.
 解放军306医院磁共振室 
关键词:Epilepsy Children Language fMRI 
分类号:R395.2
出版年,卷(期):页码:2003,11(2):157-160
摘要:

Localization of the language -dominant hemisphere with fMRI has been well-validated in epilepsy patients, and progress is being made in mapping higher -level cognitive functions, particularly language and memory.The new developments in functional imaging offer the possibility of localizing the epileptogenic focus noninvasively and mapping cognitive functions.Despite the difficulties of functional imaging in children owing to the limited cooperation that can be expected,development issue,and poor normative data,fMRI provides clinically useful information for presurgical work -up of childhood epilepsy.

Localization of the language-dominant hemisphere with fMRI has been well-validated in epilepsy patients, and progress is being made in mapping higher-level cognitive functions, particularly language and memory.The new developments in functional imaging offer the possibility of localizing the epileptogenic focus noninvasively and mapping cognitive functions.Despite the difficulties of functional imaging in children owing to the limited cooperation that can be expected,development issue,and poor normative data,fMRI provides clinically useful information for presurgical work-uPof childhood epilepsy.

基金项目:
国家攀登计划资助项目 (95-专-09)
作者简介:
参考文献:

[1] Breier JI, Simos PG, Zouridakis G, et al.Language dominance determined by magnetic source imaging: a comparison with the Wada procedure.Neurology. 1999,53(5):938-945
[2] Rutten GJ, van Rigen PC, van Veelen CW et al.Language area localization withthree-dimensional functional magnetic resonance imaging matches intrasulcal electrostimulation in Brocas area. Ann Neurol,1999, 46: 405-408
[3] Logan WJ,Smith ML,McAndrews MP et al.Lateralization of language in children with functional MRI compared to intracarotid amobarbital procedure.Epilepsia,1999, 40: 44
[4] Spreer J, Quiske A, Altenmuller DM, Arnold S, et al.Unsuspected atypical hemispheric dominance for language as determined by fMRI. Epilepsia,2001 ,42(7):957-959
[5] Springer JA, Binder JR, Hammeke TA, Language dominance in neurologically normal and epilepsy subjects: a functional fMRI study.Brain. 1999,122:2033-2046
[6] Hertz-Pannier L, Gaillard WD, Mott SH et al.Assessment of language hemispheric dominance in children with epilepsy using functional fMRI. Neurology,1997, 48: 1003-1012
[7] Jokeit H, Okujava M, Woermann FG. et al.Memory fMRI lateralizes temporal lobe epilepsy. Neurology,2001,57(10):1786-1793
[8] Muller RA, Behen ME, Rothermel RD, et al.Brain organization for language in children, adolescents, and adults with left hemisphere lesion: a PET study.Prog Neuropsychopharmacol Biol Psychiatry,1999,23(4):657-668
[9] Muller RA, Rothermel RD, Behen ME, Muzik O, et al.Language organization in patients with early and late left-hemisphere lesion: a PET study.Neuropsychologia,1999,37(5):545-557
[10] Hertz-Pannier L, Chiron C, Jambaque I et al. Late plasticity for language in a child's non-dominant hemisphere: a pre- and post-surgery fMRI study. Brain,2002, 125:361-372
[11] Staudt M, Grodd W, G Niemann G. et al.Early left periventricular brain lesions induce right hemispheric organization of speech.Neurology,2001, 47: 122-125
[12] Schlaggar BL,Brown TT,Lugar HM, et al.Functional neuroanatomical diferences between adults and school-age children in the processing of single words.Science,2002,296(5572):1476-1479
[13] Balsamo LM, Gaillard WD.The utility of functional magnetic resonance imaging in epilepsy and language. Curr Neurol Neurosci Rep,2002,2(2):142-149
[14] Gaillard WD, Balsamo L, Xu B, Grandin CB et al.Language dominance in partial epilepsy patients identified with an fMRI reading task. Neurology,2002,59(2):256-265
[15] Golby AJ, Poldrack RA, Illes J, Chen D et al.Memory lateralization in medial temporal lobe epilepsy assessed by functional MRI.Epilepsia,2002,43(8):855-863
[16] Keene DL, Logan WJ, McAndrews MP et al.A comparison of three functional MRI language paradigms in children.Epilepsia,2000, 41: 193
[17] Lantz G, Spinelli L, Menendez RG, et al.Localization of distributed sources and comparison with functional fMRI.Epileptic Disord,2001,Special Issue:45-58
[18] Chiron C, Hertz-Pannier L.Cerebral imaging in childhood epilepsy: what's new? Epileptic Disord,2001,3 Spec No 2:SI 25-36
[19] Wormann FG.The value of neuroimaging in diagnosis of epilepsy.Ther Umsch,2001,58(11):645-649
[20] Krakow K, Lemieux L, Messina D, et al.Spatio-temporal imaging of focal interictal epileptiform activity using EEG-triggered functional fMRI. Epileptic Disord,2001,3(2):67-74
[21] Ishibashi H, Simos PG, Wheless JW, et al.Localization of ictal and interictal bursting epileptogenic activity in focal cortical dysplasia: agreement of magnetoencephalography and electrocorticography.Neurol Res,2002,24(6):525-530
[22] Gaillard WD, Grandin CB, Xu B et al.Developmental aspects of pediatric fMRI: Considerations for image acquisition, analysis, and interpretation. Neuroimage,2001, 13: 239-249

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