中国临床心理学杂志

氯丙嗪、氯氮平及利培酮对精神分裂症患者生活质量影响的比较研究

作者：卞清涛谢光荣

关键词：Chlorpromazine Clozapine Risperidone Schizophrenia Quality of Life

分类号：R395.6

出版年,卷(期):页码：2003,11(2):125-127

摘要：

Objective:To explore the effect of Chlorpromazine,Clozapine and Risperidone on the quality of life in Schizophrenic patients.Methods:93 Schizophrenic patients who had recovered or significantly improved with the treatment of Chlorpromazine,Clozapine and Resperidone were evaluated with the Life Satisfaction Rating Scales(LSR)and SDSS.Results:The patients in Risperidone group showed the highest total score and item scores in the LSR and the best social functions compared with the other two groups evaluated with the SDSS(P <0.05).Muti-variables analy sis showed that the score of Life Satisfaction Rating Scale associated negatively with the score of side effects by drugs.Conclusion:Risperidone had the best effect on patient' s quality of life.

Objective:To explore the effect of Chlorpromazine,Clozapine and Risperidone on the quality of life in Schizophrenic patients.Methods:93 Schizophrenic patients who had recovered or significantly improved with the treatment of Chlorpromazine,Clozapine and Resperidone were evaluated with the Life Satisfaction Rating Scales(LSR)and SDSS.Results:The patients in Risperidone grouPshowed the highest total score and item scores in the LSR and the best social functions compared with the other two groups evaluated with the SDSS(P<0.05).Muti-variables analy sis showed that the score of Life Satisfaction Rating Scale associated negatively with the score of side effects by drugs.Conclusion:Risperidone had the best effect on patient' s quality of life.

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参考文献：

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