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摘要：
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Objective:To explore the influence of depression on heart rate variability(HRV) and short term prognosis of patients with acute myocardial infarction(AMI). Methods: 120 AMI patients were evaluated with Zung. s self- rating depression scale within 24 hours after admission.The patients were divided into depressive group(45 cases) and non- depressive group(75 cases) according to depressive index. Post- infarction angina pectoris, reinfarction, heart failure and ventricular fibrillation as well as cardiac death were observed during 4 weeks.HRV analysis with 24- hour holter of survivals was perfomed in 1 week after infarction. Results: The prevalence of post- infarction angina pectoris, ventricular fibrillation and cardiac death in depressive group was remarkably elevated compared with non- depressive group(40.0% vs 22.7%, 20.0% vs 6.7%, 17.8% vs 4.0%, respectively. P < 0.05).Multivariate logistic regression analysis results indicated that depression was independently and significantly related to the occurrence of post- infarction angina pectoris, ventricular fibrillation and cardiac death. SDNN, SDANN, RMNN and PNN50 as well as HF in depressive group were obviously reduced,whereas VLF, LF and LF/ HF were remarkedly increased compared with nondepressive group(P < 0.01 or 0.05). Correlation analysis found that depressive index was negatively related with SDNN, SDANN, RMNN, PNN50 and HF(P< 0.01), and positively correlated with VLF, LF and LF/ HF(P < 0.01). Conclusion:Depression impacts adversely HRV, and was an independent risk factor of the short term prognosis of AMI patients.
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Objective:To explore the influence of depression on heart rate variability(HRV) and short term prognosis of patients with acute myocardial infarction(AMI). Methods: 120 AMI patients were evaluated with Zung. s self-rating depression scale within 24 hours after admission.The patients were divided into depressive group(45 cases) and non-depressive group(75 cases) according to depressive index. Post-infarction angina pectoris, reinfarction, heart failure and ventricular fibrillation as well as cardiac death were observed during 4 weeks.HRV analysis with 24-hour holter of survivals was perfomed in 1 week after infarction. Results: The prevalence of post-infarction angina pectoris, ventricular fibrillation and cardiac death in depressive group was remarkably elevated compared with non-depressive group(40.0% vs 22.7%, 20.0% vs 6.7%, 17.8% vs 4.0%, respectively. P < 0.05).Multivariate logistic regression analysis results indicated that depression was independently and significantly related to the occurrence of post-infarction angina pectoris, ventricular fibrillation and cardiac death. SDNN, SDANN, RMNN and PNN50 as well as HF in depressive group were obviously reduced,whereas VLF, LF and LF/ HF were remarkedly increased compared with nondepressive group(P < 0.01 or 0.05). Correlation analysis found that depressive index was negatively related with SDNN, SDANN, RMNN, PNN50 and HF(P< 0.01), and positively correlated with VLF, LF and LF/ HF(P < 0.01). Conclusion:Depression impacts adversely HRV, and was an independent risk factor of the short term prognosis of AMI patients.
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参考文献：
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