中国临床心理学杂志

轻微认知功能损害快速识别方法的初步研究

作者：郭起浩洪震于欢丁玎周燕吕传真

单位：复旦大学附属华山医院神经内科上海200040

分类号：R749.1

出版年,卷(期):页码：2004,12(1):60-62

摘要：

目的：分析轻微认知功能损害快速识别方法。方法：以记忆减退为主诉的55岁以上老人150名，接受韦氏智力量表中文修订(WAIS-RC)和韦氏记忆量表中文修订版(WMS-RC)评估。其中智商(IQ)和记忆商(MQ)均在85以上63名，作为正常老人组；IQ在85以上、MQ为70～84的33名，作为MCI-1组；IQ在85以上、MQ为55～69的25名，作为MCI-2组；IQ和MQ均在85以下、临床表现符合DSM-Ⅳ有关阿尔茨海默病的诊断标准的有29例。结果：图片记忆和心智B得分在2个MCI组与正常老人组间最具鉴别力。对记忆轻度受损(MCI-1组)有重要识别作用的还有视觉再生记忆，对记忆较重受损(MCI-2组)有重要识别作用的还有触觉记忆、理解记忆和联想记忆。结论：图片短时记忆和心智B可以作为临床医师筛选轻微认知功能损害(MCI)的有效工具。

Objective:To analyze identify method of mild cognitive impairment.Methods:The Wechsler Adult Intelligence Scale-Chinese Revised (WAIS-RC) and Wechsler Memory Scale-Chinese Revised (WMS-RC) were examined in 150 patients with memory complaints.63 individuals whose intelligence quotient (IQ) and memory quotient (MQ) over 85 were designated as normal elderly group;and 33 individuals whose IQ scores over 85 and MQ score between 70 and 84 as mild cognitive impairment(MCI-1) group;and 25 individuals whose IQ scores over 85 and MQ scores between 55 and 69 as MCI-2 group;29 individuals whose IQ scores and MQ scores less than 85 and conformed with DSM-Ⅳ as Alzheimer disease group.Results: Picture short memory and mental control (B)showed the highest identification between the 2 MCI groups and normal elderly group.Besides,visual reproduction played an important role in mild memory decline (MCI-1) group.Tactile memory,logical memory and associated learning played an important role in moderate memory decline (MCI-2) group.Conclusion: Picture short memory and mental control (B) contribute to identify MCI speedily and effectively.

基金项目：

作者简介：

参考文献：

[1] Small SA.Age-related memory decline.Arch Neurol,2001,58:360-364.
[2] Flicker C,Ferris SH,Reisberg B.Mild cognitive impairment in the elderly:predictors of dementia.Neurology,1991,41:1006-1009.
[3] Petersen RC,Smith GE,Waring SC,et al.Mild cognitive impairment.Arch Neurol,1999,56:303-308.
[4] Petersen RC,Stevens JC,Ganguli M,et al.Practice parameter:early detection of dementia:mild cognitive impairment (an evidence-based review).Neurology,2001,56:1133-1142.
[5] Morris JC,Storandt M,Miller JP,et al.Mild cognitive impairment represents early-stage Alzheimer disease.Arch Neurol,2001,58:397-405.
[6] Taylor MJ,Heaton RK.Sensitivity and specificity of WAIS-III/WMS-III demographically corrected factor scores in neuropsychological assessment.Journal of the International Neuropsychological Society,2001,7:867-874.
[7] 龚耀先.中国修订韦氏成人智力量表.湖南地图出版社,1992.
[8] 龚耀先.修订韦氏记忆量表手册.长沙:湖南医学院,1983.
[9] Pierre C.Age-related cognitive decline,mild cognitive impairment or preclinical Alzheimer's disease? Annals of Medicine,2000,32(1):6-14.
[10] 郭起浩,洪震,吕传真.阿尔茨海默病的常用神经心理评定量表评介.中华神经科杂志,2003,36(4):310-313.
[11] 郭起浩,张明圆,Simon D,等.一组评估认知功能的神经心理测验在老人中的应用.中国临床心理学杂志,1994,2(3):155-157.

服务与反馈：

【文章下载】【加入收藏】