中国临床心理学杂志

连线测验(中文修订版)在早期识别阿尔茨海默病中的作用

作者：陆骏超郭起浩洪震史伟雄吕传真

单位：复旦大学附属华山医院神经内科上海 200040

分类号：R395.1

出版年,卷(期):页码：2006,14(2):118-120

摘要：

目的：中文修订版的连线测验(TMT)在识别轻度认知功能障碍(MCI)和轻度阿尔茨海默病(AD)中的作用。方法：对正常老人94名，遗忘型MCI组107例和轻度AD组54例进行MMSE、TMT在内的8种神经心理测验。结果：正常老人与MCI组TMT完成率均高于轻度AD组。年龄与教育程度对TMT-B的影响比TMT-A更大。TMT-A、B与MMSE、CFT模仿、CWCR、CFT回忆、AVLT延迟回忆均有显著相关性。完成TMT-A、B测验，NC组、MCI组与轻度AD组两两比较均有显著差异，TMT可以清楚的区分三组。结论：TMT对MCI病人有一定的辅助识别作用，对轻度AD病人有较强的辅助识别作用.。

Objective: To investigate the applicability of Trail making test-Chinese version in Chinese elderly patients with mild cognitive impairment(MCI) and Alzheimer's dementia(AD).Methods: 94 normal elders, 107 amnestic MCI patients and 54 patients with mild AD accepted 8 neuropsychological tests including TMT, mini-mental state examination(MMSE), etc.Results: More persons completed the whole test in normal elderly group and patients with MCI than in patients with mild AD.Age and education level have more influence on TMT-B than TMT-A.Significant relationships are found between TMT-A/B and MMSE, CFT, CWCR, and AVLT.We found significant difference among 3 groups in time for completion of TMT and the interference index.Conclution: The modified TMT is applicable for the Chinese population.It can help idenfify patients with MCI and mild AD.

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参考文献：

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