中国临床心理学杂志

伴迟发性运动障碍的慢性精神分裂症患者认知功能研究

作者：胡卫红¹ 2 江开达¹ 2 陈红芳² 丁会蓉²

单位：1. 复旦大学附属华山医院精神医学教研室上海 200040
2. 上海市精神卫生中心上海 200030

分类号：R395.2

出版年,卷(期):页码：2007,15(5):548-549

摘要：

目的：了解伴迟发性运动障碍(TD)的慢性精神分裂症患者认知功能的损害情况。方法：以82例伴TD的(TD组)、70例不伴TD的慢性精神分裂症患者(非TD组)为研究对象，两组一般情况相匹配，选用韦氏记忆测验(WMS)、威斯康星卡片分类测验(WCST)及连线测验(TMT)进行认知功能评定。结果：①两组在WMS方面比较无统计学差异。②两组在WCST方面比较，TD组错误应答数、选择错误率、错误思考时间、持续应答数及概念化水平百分数成绩均显著差于非TD组。③两组在TMT方面比较，TD组PartB耗时数显著长于非TD组，而两组PartA耗时数无显著差异。结论：伴TD的慢性精神分裂症病人存在明显的认知功能损害，且可能涉及额叶皮层。

Objective:To explore the cognitive function of chronic schizophrenic padenls with tardive dyskinesia(TD)．Methods:82 chronic schizophrenic patients with TD,70 chroinc hizophrenic patients without TD were accepted 3 neuropsychological tests including WMS，WCST and TMT．Results:Compared with non-TD group in WCST,TD group had poorer performance in the number of error responses，the selective error rate,error rate, error thinking time,the number of perservation of responses and the rate of conceptualization responses．Additionally,TD group had poorer performance in TMT—PartB．Conclusion:Chronic schizophrenie patients with TD had significantly cognitive impairment,involving the frontal cortex．

基金项目：

作者简介：

参考文献：

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