设为首页 | 加入收藏
网站首页 本刊简介 编委会 投稿指南 过刊浏览 广告合作 网上订购 下载专区 联系我们  
孕期应激对母儿影响的研究新进展
作者:王陆颖1  王新1  王若光2 3 
单位:1. 中南大学湘雅二医院妇产科  湖南 长沙 410011 
2.
 湖南中医药大学  湖南 长沙 410007 
3.
 中南大学生物科学与技术学院  湖南 长沙 410078 
关键词:孕期应激 产后抑郁症 创伤后应激障碍 皮质醇 
分类号:R173
出版年,卷(期):页码:2009,17(5):639-641
摘要:

孕期的精神社会应激会显著增高患者的CRH和皮质醇水平,造成不良妊娠结局,如早产、低体重儿、妊娠期高血压疾病。而且孕期应激与产后抑郁发生关系密切,对后代的心理、行为、中枢系统发育都有不利影响。

Pregnancy stress may significantly elevate the level of CRH and cortisol, which contributes to the bad pregnancy outcomes like premature delivery, low birth weight infant even hypertensive disorders complicating pregnancy. It also has close relationship with postpartum depression. In addition, it has a bad influence on offsprings’ mental growth, behavior development and the development of central nervous system.

基金项目:
作者简介:
参考文献:

[1] Grant KE,Compas BE,et al.Stress and child and adoles- cent psychopathology :Moving from markers to mechanisms of risk.Psychological Bulletin,2003,129:447-466
[2] Grammatopoulos DK,Chrousos GP.Functional characterist- ics of CRH receptors and potential clinical applications of CRH-receptor antagonists.Trends in endocrinology and metabolism,2002,13:436-444
[3] Hobel C,Culhane J.Role of psychosocial and nutritional stress on poor pregnancy outcome.The Journal of Nutrition,2003,133:1709S-1717S
[4] Coussons-Read ME,Okun ML,Nettles CD.Psychosocial stress increases inflammatory markers and alters cytokine production across pregnancy.Brain,Behavior,and Imm- unity,2007,21:343-350
[5] Altarac M,Strobino D.Abuse during pregnancy and stress because of abuse during pregnancy and birthweight.Journal of American Medical Women' s Association,2002,57:208-214
[6] Biernacka JB,Hanke W.The effect of occupational and non-occupational psychosocial stress on the course of preg- nancy and its outcome.Medycyna Pracy,2006,57:281-290
[7] Hilmert CJ,Schetter CD,Dominguez TP,et al.Stress and blood pressure during pregnancy:racial differences and associations with birthweight.Psychosomatic Medicine,2008,70:57-64
[8] Glynn LM,Schetter CD,Hobel CJ,et al.Pattern of perce- ived stress and anxiety in pregnancy predicts preterm birth.Health psychology. Official Journal of the Division of Health Psychology,American Psychological Association,2008,27:43-51·640· Chinese Journal of Clinical Psychology Vol.17 No.52009
[9] Leeners B,Neumaier-Wagner P,Kuse S,et al.Emotional stress and the risk to develop hypertensive diseases in pre- gnancy.Hypertension in pregnancy . Official Journal of the International Society for the Study of Hypertension in Pregnancy,2007,26:211-226
[10] Nierop A,Bratsikas A,Klinkenberg A,et al.Prolonged salivary cortisol recovery in second-trimester pregnant women and attenuated salivary alpha-amylase responses to psychosocial stress in human pregnancy.The Journal of Clinical Endocrinology and Metabolism,2006,91:1329-1335
[11] Bjelica A.Pregnancy as a stressful life event and strategies for coping with stress in women with pregnancy-induced hypertension.Medicinski Pregled,2004,57:363-368
[12] Williams D.Pregnancy :A stress test for life.Current Opinion in Obstetrics and Gynecology,2003,15:465-471
[13] Nierop A,Bratsikas A,Zimmermann R,et al.Are stress induced cortisol changes during pregnancy associated with postpartum depressive symptoms? Psychosomatic Medicine,2006,68:931-937
[14] Grote NK,Bledsoe SE.Predicting postpartum depressive symptoms in new mothers:the role of optimism and stress frequency during pregnancy.Health and Social Work,2007,32:107-118
[15] Urizar GG Jr,Milazzo M,Le HN,et al.Impact of stress reduction instructions on stress and cortisol levels during pregnancy.Biological Psychology,2004,67:275-282
[16] Vieten C,Astin J.Effects of a mindfulness-based inter- vention during pregnancy on prenatal stress and mood:Results of a pilot study.Archives of Women' s Mental Health,2008,11:67-74
[17] Otten W,Kanitz E,Tuchscherer M,et al.Effects of adreno- corticotropin stimulation on cortisol dynamics of pregnant gilts and their fetuses:Implications for prenatal stress studies.Theriogenology,2004,61:1649-1659
[18] Gotz AA,Stefanski V.Psychosocial maternal stress during pregnancy affects serum corticosterone,blood immune para- meters and anxiety behaviour in adult male rat offspring.Physiology and Behavior,2007,90:108-115
[19] Gotz AA,Wolf M,Stefanski V.Psychosocial maternal stress during pregnancy:Effects on reproduction for F0 and F1 generation laboratory rats.Physiology and Behavior,2008,93:1055-1060
[20] Egliston KA,McMahon C,Austin MP.Stress in pregnancy and infant HPA axis function:Conceptual and methodolog- ical issues relating to the use of salivary cortisol as an outcome measure.Psychoneuroendocrinology,2007,32:1-13
[21] Austin MP,Hadzi-Pavlovic D,Leader L,et al.Maternal trait anxiety,depression and life event stress in pregnancy:Re- lationships with infant temperament.Early Human Deve- lopment,2005,81:183-190
[22] Mohler E,Parzer P,Brunner R,et al.Emotional stress in pregnancy predicts human infant reactivity.Early Human Development,2006,82:731-737
[23] van der Wal MF,van Eijsden M,Bonsel GJ.Stress and em- otional problems during pregnancy and excessive infant crying.Journal of Development and Behavioral Pediatrics,2007,28:431-437
[24] Rodriguez A,Bohlin G.Are maternal smoking and stress during pregnancy related to ADHD symptoms in children? Journal of Child Psychology and Psychiatry,and Allied Disciplines,2005,46:246-254
[25] Grizenko N,Shayan YR,Polotskaia A,et al.Relation of maternal stress during pregnancy to symptom severity and response to treatment in children with ADHD.Journal of Psychiatry and Neuroscience,2008,33:10-16
[26] Rieger M,Pirke KM,Buske-Kirschbaum A,et al.Influence of stress during pregnancy on HPA activity and neonatal behavior.Annals of New York Academic of Sciences,2004,1032:228-230
[27] Bergman K,Sarkar P,O' Connor TG,et al.Maternal stress during pregnancy predicts cognitive ability and fearfulness in infancy.Journal of American Academy of Child and Adolescent Psychiatry,2007,46:1454-1463
[28] Schneider ML,Roughton EC,Koehler AJ,et al.Growth and development following prenatal stress exposure in primates:An examination of ontogenetic vulnerability.Child Develop- ment,1999,70:263-274
[29] Ryzhavskii BY,Vasil' eva EV,Sokolova TV.Morphology of the cerebellum in the progeny of female rats exposed to long-term emotional stress before pregnancy.Bulletin of Experimental Biology and Medicine,2003,135:206-208
[30] Murmu MS,Salomon S,Biala Y,et al.Changes of spine density and dendritic complexity in the prefrontal cortex in offspring of mothers exposed to stress during pregnancy.The European Journal of Neuroscience,2006,24:1477-1487
[31] Hirst JJ,Yawno T,Nguyen P,et al.Stress in pregnancy activates neurosteroid production in the fetal brain.Neuro- endocrinology,2006,84:264-274
[32] Seng JS,Oakley DJ,Sampselle CM,et al.Posttraumatic stress disorder and pregnancy complications.Obstetrics and Gynecology,2001,97:17-22
[33] Yehuda R,Engel SM,Brand SR,et al.Transgenerational effects of posttraumatic stress disorder in babies of mothers exposed to the World Trade Center attacks during pregn- ancy.The Journal of Clinical Endocrinology and Metabo- lism,2005,90:4115-4118
[34] Laplante DP,Barr RG,Brunet A,et al.Stress during pregn- ancy affects general intellectual and language functioning in human toddlers.Pediatric Research,2004,56:400-410
[35] Rogal SS,Poschman K,Belanger K,et al.Effects of post- traumatic stress disorder on pregnancy outcomes.Journal of Affective Disorders,2007,102:137-143

服务与反馈:
文章下载】【加入收藏
您是第访问者

《中国临床心理学杂志》编辑部
地址:湖南省长沙市中南大学湘雅二医院内, 410011
电 话:0731-85292472    电子邮件:cjcp_china@163.com
本系统由北京博渊星辰网络科技有限公司设计开发 技术支持电话:010-63361626