中国临床心理学杂志

额叶肿瘤患者执行功能研究

作者：彭立辉郭立新李江卢明

分类号：R395.1

出版年,卷(期):页码：2010,18(6):717-719

摘要：

目的:①研究额叶肿瘤患者的执行功能是否存在损害。②比较左额叶肿瘤患者与右额叶肿瘤患者的执行功能损害差异。方法:27名左额叶肿瘤患者、27名右额叶肿瘤患者、30名正常对照者,选用威斯康辛卡片分类测验(WCST)和连线测验进行执行功能评估。结果:①在WCST的完成分类数、完成第一次分类所需应答数、概念化水平百分数、持续性应答数以及持续性错误百分数5个指标上,左额叶组均显著差于右额叶组(P<0.05)以及正常组(P<0.05);而右额叶组的5个指标也显著的差于正常组(P<0.05)。②连线测验A的完成时间,连线测验B的完成时间与错误数上,左额叶组均显著差于右额叶组(P<0.05)和正常组(P<0.05);右额叶组在连线A完成时间与正常组没有显著差异(P=0.525),但在连线B完成时间和错误数上也显著差于正常组。结论:额叶肿瘤严重损害了成年人的执行功能,左额叶肿瘤对执行功能的损害程度更严重。

Objective:To study whether the executive function is impaired in patients with frontal lobe tumor,and to compare the differences of the impairments between the patients with left frontal lobe tumor and those with right frontal lobe tumor.Methods:Three groups include 27 patients with left frontal lobe tumor,27 patients with right frontal lobe tumor,and 30 normal adults were measured by Wisconsin Card Sort ing Test(WCST),Trail Making Test(TMT).Results:①There are significant defferences between the left frontal lobe group(LF) and the right frontal lobe group(RF) and normal controls(NC) in the indicators of WCST,including categories achieved(CA),the number of trials to complete the first category(R1st),perserative responses(PR),percent of perserative errors(PE%),and the percent of the conceptual level responses(CLR%).②The time of TMT-A,The time of TMT-B,and errors of TMT-B are signicant between LF and RF and NC.Conclusion:The executive function is impaired by frontal lobe tumors,and the executive function in patients with left frontal lobe tumors is more impaired compared to that of those with right frontal lobe tumors.

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参考文献：

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