中国临床心理学杂志

阿尔茨海默病和血管性痴呆的精神行为症状比较

作者：王琦毛礼炜刘娟赵合庆刘春风李文

分类号：R749.1

出版年,卷(期):页码：2011,19(4):486-488

摘要：

目的：探讨阿尔茨海默病(AD)和血管性痴呆(VaD)患者精神行为症状(BPSD)特点及其诊断价值。方法：用AD病理行为评分表(BEHAVE-AD)对40例AD和42例VaD患者进行评定。结果：两组患者BPSD总发生率和BE-HAVE-AD总分差异均无统计学意义(P>；0.05)。AD组行为紊乱、攻击行为发生率(分别为45%与50%)及严重程度(评分分别为6.08±0.90分，4.60±1.27分)，高于VaD组(发生率分别为16.67%与23.81%，严重程度评分分别为5.69±1.70分，3.50±1.58分)，差异具有统计学意义(P<0.05)；VaD组的情感障碍发生率(64.29%)及严重程度(3.52±0.85分)高于AD组(42.50%，2.53±1.23分)，差异具有统计学意义(P<0.05)。结论：AD与VaD患者的精神行为症状呈现不同的特点，AD患者行为紊乱、攻击行为表现突出，VaD患者情感障碍表现突出。

Objective:investigate behavioral and psychological symptoms of dementia (BPSD) characteristics in patientswith Alzhermer’s disease(AD) and vascular dementia(VaD).Methods:BPSD in 40 patients with AD and 42 patientswith VaD were assessed by rating scale of the behavioral pathology in Alzheimer’s disease (BEHAVE-AD).The resultswere compared and analyzed.Results:The difference of the overall incidence of BPSD and the total BEHAVE-AD scorein the two groups was not statistically significant (P>0.05).The incidence and severity of behavioral disorders （45% and6.08±0.90 points） and aggressive behavior （50%,4.60±1.27 points） in AD group were higher than those in VaD group（incidence:16.67% and 23.81%,severity score:5.69±1.70 points and 3.50±1.58 points）,and the difference was statisticallysignificant (P＜0.05).The incidence and severity of affective disorders in VaD （64.29% and 3.52±0.85 points） groupwas higher than that in AD group （42.50%,2.53±1.23 points）,and the difference was statistically significant (P<0.05).Conclusion:Patients with AD and VaD show different characteristics in BPSD;patients with AD were prominent in behaviordisorder and aggressive behavior while patients with VaD prominent in affective disorders.

基金项目：

苏州市科技发展计划资助项目(YJS0923)

作者简介：

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