Objective: To investigate the clinical characteristics of anxiety, depression and alexithymia in patients with chronic widespread pain(CWP) and the relationship between alexithymia and anxiety and depression. Methods: 118 patients with CWP were enrolled and tested by the Visual Analogue Scale(VAS) for pain intensity, the 20-item Toronto Alexithymia Scale(TAS-20), the Spielberger Trait Anxiety Inventory(TAI), and the 13-item Beck Depression Inventory(BDI-13). Results: 45 patients without medical accountings were diagnosed with somatoform disorder, depression, anxiety disorders and adjustment disorders. 31 patients with CWP were diagnosed as alexithymic. Compared to the CWP patients with medical accountings, the patients without medical accountings showed significantly higher scores in the total score of TAS-20, the TAI score and the BDI-13 score. Compared with the nonalexithymic patients with CWP, the alexithymic patients with CWP had significantly higher scores in the total score of TAS-20, the TAI score and the VAS score. The total score of TAS-20, the factor DIF score and the factor DDF score were significantly related to the BDI-13 score in patients with CWP(r= 0.294, 0.303 and 0.248 respectively,P<0.01). Conclusion: The CWP patients without medical accountings have higher prevalence of alexithymia and higher levels of anxiety and depression.
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